Does FDG PETCT Scan has Role in Urinary Bladder Urothelial Carcinoma.

Document Type : Editorial

Authors

1 Professor of Nuclear Medicine, Faculty of Medicine, Cairo University.

2 Nuclear medicine department , national cancer institute , Cairo university , Egypt

Abstract

Bladder Cancer is a widespread common disease in EGYPT, that is ranked as the 10th most commonly, diagnosed form of cancer globally. In standard clinical practice, preoperative staging of muscle-invasive urinary bladder cancer, performing computed tomography (CT) scan of the chest, abdomen, and pelvis as a part of pre-operative assessment. Also, pelvic MRI can also be done. FDG-PET scan in comparison to computed tomography (CT) scan in patients with urothelial carcinoma may help in improving staging and hence better prognosticate and change of therapy. FDG PET/CT could detect extra-pelvic metastatic lesions with higher sensitivity as compared to CT. FDG-PET/CT can help to determine the response of primary tumor bladder Cancer in patients with muscle-invasive bladder cancer and thus can more accurately predict prognosis. F-FDG PET/CT using SUVmax of LNs is a useful tool for preoperative evaluation of pelvic LN metastases from invasive bladder cancer and may contributes for the selection of patients treatment management. PET/CT had higher sensitivity and specificity in identifying complete pathologic response and detection of chemo-sensitive tumors. Also FDG-PET/CT can help determine the response of primary tumor to NAC in patients with muscle-invasive bladder cancer and thus can more accurately predict prognosis.
Conclusion: PET/CT may help in improving staging and detection of extra-pelvic metastatic lesions with higher sensitivity as compared to CT also may help in evaluation of pelvic LN metastases from invasive bladder cancer.

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